Molar mass 127.5715 g/mol Density 1.43 g/cm³ Appearance pale yellow solid | Formula C6H6ClN Boiling point 232 °C | |
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4-Chloroaniline is an organochlorine compound with the formula ClC6H4NH2. This pale yellow solid is one of several known chloroanilines.
Contents
Preparation
4-Chloroaniline is not prepared from aniline, which tends to overchlorinate. Instead, it is prepared by hydrogenation of 4-nitrochlorobenzene, which in turn is prepared by nitration of chlorobenzene.
Uses
4-Chloroaniline is an important building block used in the chemical industry for the production of pesticides, drugs, and dyestuffs. It is a precursor to the widely used antimicrobial and bacteriocide chlorhexidine and is used in the manufacture of pesticides, including pyraclostrobin, anilofos, monolinuron and chlorphthalim. Some benzodiazepine drugs use 4-chloroaniline in their manufacture.
4-Chloroaniline can be used to make dorastine (antihistamine), lorcainide (antiarrhythmic) and Ontianil.
