3 deoxy manno octulosonate 8 phosphatase

In enzymology, a 3-deoxy-manno-octulosonate-8-phosphatase (EC 3.1.3.45) is an enzyme that catalyzes the chemical reaction

3-deoxy-D-manno-octulosonate 8-phosphate + H₂O ⇌ 3-deoxy-D-manno-octulosonate + phosphate

Thus, the two substrates of this enzyme are 3-deoxy-D-manno-octulosonate 8-phosphate and H₂O, whereas its two products are 3-deoxy-D-manno-octulosonate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase. This enzyme participates in lipopolysaccharide biosynthesis.