23S rRNA (adenine2503 C2) methyltransferase

23S rRNA (adenine²⁵⁰³-C²)-methyltransferase (EC 2.1.1.192, RlmN, YfgB, Cfr) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine²⁵⁰³-C²)-methyltransferase. This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + adenine²⁵⁰³ in 23S rRNA ⇌ ^{S-adenosyl-L-homocysteine} + L-methionine + 5'-deoxyadenosine + 2-methyladenine²⁵⁰³ in 23S rRNA

23S rRNA (adenine²⁵⁰³-C²)-methyltransferase contains an [4Fe-4S] cluster.