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23S rRNA (uridine2479 2' O) methyltransferase

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EC number
  
2.1.1.208

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

23S rRNA (uridine2479-2'-O)-methyltransferase (EC 2.1.1.208, AviRb) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (uridine2479-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + uridine2479 in 23S rRNA ⇌ S-adenosyl-L-homocysteine + 2'-O-methyluridine2479 in 23S rRNA

Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis.

References

23S rRNA (uridine2479-2'-O)-methyltransferase Wikipedia
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