23S rRNA (adenine1618 N6) methyltransferase

23S rRNA (adenine¹⁶¹⁸-N⁶)-methyltransferase (EC 2.1.1.181, rRNA large subunit methyltransferase F, YbiN protein, rlmF (gene), m6A1618 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine¹⁶¹⁸-N⁶)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine¹⁶¹⁸ in 23S rRNA ⇌ S-adenosyl-L-homocysteine + N⁶-methyladenine¹⁶¹⁸ in 23S rRNA

The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit.