2015–16 Oklahoma State Cowgirls basketball team

The 2015–16 Oklahoma State Cowgirls basketball team will represent Oklahoma State University in the 2015–16 college basketball season. It will be head coach Jim Littell's fifth season at Oklahoma State. The Cowgirls are members of the Big 12 Conference and will play their home games at the Gallagher-Iba Arena. They finished the season 21–10, 11–7 in Big 12 play to finish in a tie for fourth place. They lost in the quarterfinals of the Big 12 Women's Tournament to Oklahoma. They received at-large bid of the NCAA Women's Basketball Tournament where they lost in the first round to St. Bonaventure.