2 iminoacetate synthase

Updated on Dec 18, 2024

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EC number 4.1.99.19 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

2-iminoacetate synthase (EC 4.1.99.19, thiH (gene)) is an enzyme with systematic name L-tyrosine 4-methylphenol-lyase (2-iminoacetate-forming). This enzyme catalyses the following chemical reaction

L-tyrosine + S-adenosyl-L-methionine + reduced acceptor ⇌ 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H⁺

This enzyme binds a 4Fe-4S cluster.

References

2-iminoacetate synthase Wikipedia

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