2 hydroxy 3 oxopropionate reductase

In enzymology, a 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) is an enzyme that catalyzes the chemical reaction

The 3 substrates of this enzyme are (R)-glycerate, NAD⁺, and NADP⁺, whereas its 4 products are 2-hydroxy-3-oxopropanoate, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (R)-glycerate:NAD(P)⁺ oxidoreductase. This enzyme is also called tartronate semialdehyde reductase. This enzyme participates in glyoxylate and dicarboxylate metabolism.