Girish Mahajan (Editor)

2,6 Dimethylpiperidine

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Covid-19
Related compounds  Piperidine
Molar mass  113.2 g/mol
Boiling point  113.2 °C
Formula  C7H15N
Density  840 kg/m³
Appearance  Colorless liquid
2,6-Dimethylpiperidine wwwsigmaaldrichcomcontentdamsigmaaldrichstr

2,6-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Three stereoisomers exist: the achiral (R,S)-isomer and the chiral (R,R)/(S,S) enantiomeric pair. Dimethylpiperidines are derivatives of the heterocycle piperidine, wherein two hydrogen atoms are replaced by methyl groups.

The 2,6-dimethylpiperidines are prepared by reduction of 2,6-dimethylpyridine (2,6-lutidine). The achiral isomer is the predominant isomer produced in this reaction.

The 2,6-dimethylpiperidines are of interest for their conformational properties. The (R,S)-isomer exists largely in the chair conformation with equatorial methyl groups. The (R,R)/(S,S)-isomers are attractive chiral secondary amine building blocks.

References

2,6-Dimethylpiperidine Wikipedia


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