|Covid-19|January – Maine Central Railroad predecessor Androscoggin and Kennebec Railroad is completed between Auburn, Maine and Waterville, Maine.
May 13 – The Mecklenburgische Eisenbahngesellschaft opens the Rostock-Bützow-Bad Kleinen and Güstrow-Bützow railway lines in northern Germany.
July 1 – Joseph Hamilton Beattie succeeds John Viret Gooch as locomotive engineer for London and South Western Railway.
July 4 - Chile : The first section of the Copiapó-Caldera railway line - the first one in South America - between Caldera and Monte Amargo was inaugurated on July 4 of 1850 in honour of the nationality of William Wheelwright, the American business man responsible for the project.
August 29 – Robert Stephenson's Royal Border Bridge for the York, Newcastle and Berwick Railway at Berwick-upon-Tweed, England is opened by Queen Victoria.
October 19 – Robert Stephenson's Britannia Bridge, completing the Chester and Holyhead Railway over the Menai Strait in North Wales, is opened.
November 19 – Farmers around Detroit, Michigan, burn down the Michigan Central Railroad's freight house in Detroit; the farmers were angry at the railroad's policy regarding not reimbursing them for livestock killed by trains when the stock wandered onto the tracks.
November 20 – The first train operates on the Milwaukee, St. Paul and Pacific Railroad, a predecessor of the Milwaukee Road.
The Richmond and Danville Railroad begins operation in Virginia.
Construction begins on the first transcontinental railroad to be completed, the Panama Railway.
February 27 – Henry Huntington, nephew of Collis P. Huntington and executive in charge of Pacific Electric in the early part of the 20th century (d. 1927).
November 19 – Jule Murat Hannaford, president of Northern Pacific Railway 1913–1920, is born (d. 1934)
July 7 – Timothy Hackworth, English steam locomotive builder (b. 1786).
1850 in rail transport Wikipedia
This article lists events related to rail transport that occurred in 1850.