Supriya Ghosh (Editor)

14 Cinnamoyloxycodeinone

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Covid-19
CAS Number  751-01-9
ChemSpider  4942728
3D model (Jmol)  Interactive image
PubChem CID  6438241
Formula  C27H25NO5
Molar mass  443.49 g/mol
14-Cinnamoyloxycodeinone httpsuploadwikimediaorgwikipediacommonsthu

14-Cinnamoyloxycodeinone is the most potent example in a series of opiate analgesic drugs discovered in the 1960s, with > ×100 times the potency of morphine. It is a derivative of hydroxycodeinone, being the 14-cinnamate ester. In another paper, Buckett assigns the potency as 177 with a range (depending on animal and test) of ×101 - ×310. It may be of interest to researchers that the allyl group in this compound and in allylprodine overlay very closely.

References

14-Cinnamoyloxycodeinone Wikipedia


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