|EC number 22.214.171.124|
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|CAS number 9054-77-7|
BRENDA BRENDA entry
KEGG KEGG entry
In enzymology, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 126.96.36.199) is an enzyme that catalyzes the chemical reaction1-pyrroline-4-hydroxy-2-carboxylate + H2O
Thus, the two substrates of this enzyme are 1-pyrroline-4-hydroxy-2-carboxylate and H2O, whereas its two products are 2,5-dioxopentanoate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing). This enzyme is also called HPC deaminase. This enzyme participates in arginine and proline metabolism.