|EC number 184.108.40.206|
IntEnz IntEnz view
ExPASy NiceZyme view
|CAS number 9054-77-7|
BRENDA BRENDA entry
KEGG KEGG entry
In enzymology, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 220.127.116.11) is an enzyme that catalyzes the chemical reaction1-pyrroline-4-hydroxy-2-carboxylate + H2O
Thus, the two substrates of this enzyme are 1-pyrroline-4-hydroxy-2-carboxylate and H2O, whereas its two products are 2,5-dioxopentanoate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing). This enzyme is also called HPC deaminase. This enzyme participates in arginine and proline metabolism.