EC number 3.5.99.7 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 69553-48-6 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a 1-aminocyclopropane-1-carboxylate deaminase (EC 3.5.99.7) is an enzyme that catalyzes the chemical reaction
1-aminocyclopropane-1-carboxylate + H2OThus, the two substrates of this enzyme are 1-aminocyclopropane-1-carboxylate and H2O, whereas its two products are 2-oxobutanoate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing). This enzyme is also called 1-aminocyclopropane-1-carboxylate endolyase (deaminating). This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1RQX, 1TYZ, 1TZ2, 1TZJ, 1TZK, and 1TZM.