Neha Patil (Editor)

1 aminocyclopropane 1 carboxylate deaminase

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EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  69553-48-6
KEGG  KEGG entry

In enzymology, a 1-aminocyclopropane-1-carboxylate deaminase (EC is an enzyme that catalyzes the chemical reaction

1-aminocyclopropane-1-carboxylate + H2O 2-oxobutanoate + NH3

Thus, the two substrates of this enzyme are 1-aminocyclopropane-1-carboxylate and H2O, whereas its two products are 2-oxobutanoate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing). This enzyme is also called 1-aminocyclopropane-1-carboxylate endolyase (deaminating). This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1RQX, 1TYZ, 1TZ2, 1TZJ, 1TZK, and 1TZM.


1-aminocyclopropane-1-carboxylate deaminase Wikipedia