EC number 3.1.1.47 ExPASy NiceZyme view | CAS number 76901-00-3 | |
In enzymology, a 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) is an enzyme that catalyzes the chemical reaction
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2OThus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine and H2O, whereas its two products are 1-alkyl-sn-glycero-3-phosphocholine and acetate.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1BWP, 1BWQ, 1BWR, 1ES9, 1FXW, 1VYH, and 1WAB.