Formula C4H9Br Appearance Colourless liquid | Density 1.27 g/cm³ | |
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Related alkanes | ||
Haloalkanes 3 1 bromobutane preparation and purification
1-Bromobutane is the organobromine compound with the formula CH3(CH2)3Br. It is a colorless liquid, although impure samples appear yellowish. It is insoluble in water, but soluble in organic solvents. It is a primarily used as a source of the butyl group in organic synthesis. It is one of several isomers of butyl bromide.
Contents
- Haloalkanes 3 1 bromobutane preparation and purification
- Williamson ether synthesis using 1 bromobutane and potassium tert butoxide
- Synthesis
- Reactions
- References
Williamson ether synthesis using 1 bromobutane and potassium tert butoxide
Synthesis
It is prepared from butanol by treatment with hydrobromic acid]]:
CH3(CH2)3OH + HBr → CH3(CH2)3Br + H2OReactions
As a primary haloalkane, it is prone to SN2 type reactions. It is commonly used as an alkylating agent. When combined with magnesium metal in dry ether, it gives the corresponding Grignard reagent. Such reagents are used to attach butyl groups to various substrates.
1-Bromobutane is the precursor to n-butyllithium:
2 Li + C4H9X → C4H9Li + LiX where X = Cl, Br
The lithium for this reaction contains 1-3% sodium. When bromobutane is the precursor, the product is a homogeneous solution, consisting of a mixed cluster containing both LiBr and LiBu.
