Rahul Sharma (Editor)

1,3 Diaminopropane

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3DMet  B00214
Formula  C3H10N2
Molar mass  74.1249 g/mol
Abbreviations  TMEDA
Density  880 kg/m³
Appearance  Colourless liquid
1,3-Diaminopropane wwwbmrbwiscedumetabolomicsstandards13diami

Related alkanamines  EthylamineEthylenediaminePropylamineIsopropylamine1,2-DiaminopropaneIsobutylaminetert-Butylaminen-Butylaminesec-ButylaminePutrescine
Related compounds  2-Methyl-2-nitrosopropane

1,3-Diaminopropane, also known as trimethylenediamine, is a simple diamine with the formula (CH2)3(NH2)2. A colourless liquid with a fishy odor, it is soluble in water and many polar organic solvents. It is isomeric with 1,2-diaminopropane. Both are building blocks in the synthesis of heterocycles, such as those used in textile finishing, and coordination complexes. It is prepared by the amination of acrylonitrile followed by hydrogenation of the resulting aminopropionitrile.

The potassium salt was used in the alkyne zipper reaction.

Known uses of 1,3-Diaminopropane is in the synthesis of piroxantrone and Losoxantrone.


1,3-Diaminopropane is toxic on skin exposure with an LD50 of 177 mg kg−1 (dermal, rabbit)


1,3-Diaminopropane Wikipedia