In enzymology, a (4S)-limonene synthase (EC 184.108.40.206) is an enzyme that catalyzes the chemical reactiongeranyl diphosphate
Hence, this enzyme has one substrate, geranyl diphosphate, and two products, (−)-(4S)-limonene and diphosphate.
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [cyclizing, (−)-(4S)-limonene-forming]. Other names in common use include (−)-(4S)-limonene synthase, 4S-(−)-limonene synthase, geranyldiphosphate diphosphate lyase (limonene forming), geranyldiphosphate diphosphate lyase [cyclizing,, and (4S)-limonene-forming]. This enzyme participates in monoterpenoid biosynthesis.