'Ali Khalil, also known as Ali-Sultan , was the khan (r.1342/1343) of the Chagatai Khanate. He was a descendant of Qadan, son of the second Great Khan Ögedei.
'Ali attacked the ordo (palace) of Yesun Temur and usurped the throne. He was the first and last one who had restored the Ögedeid authority over the Chagatai Khanate since the reigns of Kaidu and his son Chapar. During his reign, Islam fully absorbed the Chagatai Mongols and 'Ali persecuted non-Muslim religions.