Zucker is a German surname meaning "sugar". Notable people with the surname include:
Anita Zucker, American businesswoman and philanthropist
David Zucker (filmmaker), American film director
Gerhard Zucker, German businessman and rocket engineer
Harold Zucker, Australian rules footballer
Jason Zucker, American ice hockey player
Jeff Zucker, American television producer and president of CNN
Jerry Zucker (film director), American film director
Jerry Zucker (businessman), American businessman
Kenneth Zucker, Canadian psychologist
Monte Zucker (died 2007), American photographer
Paul Zucker, German-born architect, art historian, art critic and author
Steven Zucker, American mathematician