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Zincke–Suhl reaction

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Zincke–Suhl reaction

The Zincke–Suhl reaction is a special case of a Friedel-Crafts alkylation and was first described by Theodor Zincke and Suhl.

The classic example of this reaction is the conversion of p-cresol to a cyclohexadienone (with the aid of aluminium chloride as a catalyst and tetrachloromethane as a solvent). Melvin Newman, a scientist from the U.S. intensively studied the reaction in the 1950s and reported several improved procedures as well as mechanistic studies.

The reaction product is a starting material in the dienol benzene rearrangement.

References

Zincke–Suhl reaction Wikipedia


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