Zena is a feminine given name. Notable people with the name include:
Zena Dare (1887–1975), English singer and actressZena Grey (born 1988), American actressZena Keefe (1896–1977), American silent film actressZena Marshall (1925–2009), British actressZena McNally (born 1979), English singerZena Skinner (born 1927), English chef and television presenterZena Tooze (born 1955), Canadian biologist and conservationistZena Tsarfin, American journalistZena Walker (1934–2003), English actressZena Werb (born 1945), cell biologist at University of California, San Francisco