Zajc is a surname. Notable people with the surname include:
Dane Zajc (1929–2005), Slovene poet
Gorazd Zajc (born 1987), Slovenian footballer
Ivan Zajc (1832–1914), Croatian composer, conductor, director and teacher
Tina Zajc (born 1983), won the Slovenia national beauty contest, Miss Slovenia 2003
William Allen Zajc, U.S. physicist and professor at Columbia University in New York, NY, USA