Species Human Entrez 118813 | Human Mouse Ensembl ENSG00000155256 | |
Aliases ZFYVE27, PROTRUDIN, SPG33, zinc finger FYVE-type containing 27 External IDs MGI: 1919602 HomoloGene: 16939 GeneCards: ZFYVE27 | ||
Zinc finger, FYVE domain containing 27 is a protein that in humans is encoded by the ZFYVE27 gene.
Function
This gene encodes a protein with several Transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote Neuriteformation. A mutation in this gene has been reported to be associated with Hereditary spastic paraplegia, however the Pathogenicity of the mutation, which may simply represent a Polymorphism (biology), is unclear. [provided by RefSeq, Mar 2010].
References
ZFYVE27 Wikipedia(Text) CC BY-SA