Yoshitsugu is a masculine Japanese given name. Notable people with the name include:
Hatakeyama Yoshitsugu (1552–1586), Japanese daimyo of the Sengoku period, 14th head of the Nihonmatsu clan of MutsuMaeba Yoshitsugu (1541–1574), retainer beneath the clan of Asakura throughout the late Sengoku period of Feudal JapanMiyoshi Yoshitsugu, samurai of the Sengoku period who was practically the last head of Miyoshi clanOtani Yoshitsugu (1559–1600), Japanese samurai of the Sengoku period though Azuchi-Momoyama PeriodTokugawa Yoshitsugu (1836–1849), Japanese daimyo of the Edo period, who ruled the Owari DomainYoshitsugu Harada (born 1952), Japanese politician of the Liberal Democratic Party, a member of the House of Representatives in the DietYoshitsugu Matsuoka Japanese voice actor from Hokkaido, Japan.Yoshitsugu Saito (1890–1944), lieutenant general in the Imperial Japanese Army during World War II