Yoshihisa is a masculine Japanese given name. Notable people with the name include:
Amago Yoshihisa (1540–1610), Japanese warlordAshikaga Yoshihisa (1465–1489), 9th shogun of the Ashikaga shogunatePrince Kitashirakawa Yoshihisa (1847–1895), the 2nd head of a collateral branch of the Japanese imperial familyShimazu Yoshihisa (1533–1611), daimyo of Satsuma Province and the eldest son of Shimazu TakahisaYoshihisa Furukawa (born 1965), Japanese politician of the Liberal Democratic PartyYoshihisa Hirano (born 1971), Japanese composerYoshihisa Taira (1937–2005), Japanese-born French composerYoshihisa Hirano (baseball) (born 1984), professional Japanese baseball playerYoshihisa Inoue (born 1947), Japanese politician of the New Komeito PartyYoshihisa Ishida (born 1944), retired male shot putter and hammer thrower from JapanYoshihisa Naruse (born 1985), pitcher for the Chiba Lotte Marines of Nippon Professional BaseballYoshihisa Tabuchi, the president of Nomura Securities between 1985 and 1991Yoshihisa Yamamoto (scientist) (born 1950), Japanese scientist and engineerYoshihisa Yamamoto (wrestler) (born 1970), Japanese professional mixed martial arts competitor and professional wrestler