Trisha Shetty (Editor)

XLR 12

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Legal status
  
CA: Schedule II

PubChem CID
  
11559386

3D model (Jmol)
  
Interactive image

ChemSpider ID
  
9734160

CAS Number
  
895155-78-9

Formula
  
C20H24F3NO

Molar mass
  
351.405 g/mol

XLR-12 httpsuploadwikimediaorgwikipediacommonsthu

XLR-12 is an indole-based synthetic cannabinoid drug that was invented by Abbott Laboratories in 2006. It is an analogue of XLR-11 where the 5-fluoropentyl chain has been replaced with a 4,4,4-trifluorobutyl chain. XLR-12 is relatively highly selective for the CB2 receptor, with a Ki of 0.09 nM and 167x selectivity over the related CB1 receptor, however it still retains appreciable affinity for CB1 with a Ki of 15 nM.

XLR-12 is illegal in Hungary and Japan.

References

XLR-12 Wikipedia
(Text) CC BY-SA