Symbol XK Entrez 7504 OMIM 314850 | Alt. symbols XKR1, Kx, X1k HUGO 12811 PDB BAE48708 | |
XK (also known as Kell blood group precursor) is a protein found on human red blood cells and other tissues which is responsible for the Kx antigen which helps determine a person's blood type.
Contents
Clinical significance
The Kx antigen plays a role in matching blood for blood transfusions.
Mutation of XK protein may lead to McLeod syndrome, a multi-system disorder characterized by hemolytic anemia, myopathy, acanthocytosis, and chorea.
XK is located on the X chromosome and absence of the XK protein is an X-linked disease.
Function
XK is a membrane transport protein of unknown action.
References
XK (protein) Wikipedia(Text) CC BY-SA