Wrigley is an English surname originating in the county of Lancashire.
Alan Wrigley (born 1931), Australian writer and commentator on topics related to intelligence, defence and security
Arthur Wrigley (1912–65), English cricket scorer and statistician
Bernard Wrigley (born 1948), English singer, actor and comedian
David Wrigley (born 1980), Canadian ice hockey player
David Wrigley (doctor), English general practitioner
Derek Fuller Wrigley (born 1924), British-born Australian architect
Drew Wrigley (born 1965), American politician
Edgar Wrigley (1886−1958), New Zealand rugby footballer who represented his country in both rugby union and rugby league
George Weston Wrigley (1847–1907), Canadian journalist and social reformer
Henry Wrigley (1892–1987), Senior commander in the Royal Australian Air Force (RAAF)
Hugh Wrigley (1891–1980), Senior officer of the Australian Army
Kurt Wrigley (born 1969), Australian rugby league player
Leslie James Wrigley (1875–1933), Australian academic and educationalist
Robert Wrigley (born 1951), American poet and educator
Stephen Wrigley (born 1987), Australian rules football player
Sylvia Spruck Wrigley (born 1968), American/German writer of science fiction, fantasy and aviation non-fiction
Tony Wrigley (born 1931), Historical demographer
Wilf Wrigley (born 1949), English soccer player
Zeke Wrigley (1874–1952), Baseball player