Worcester is an English surname. Notable people with the surname include:
Dean Conant Worcester (1866–1924), American zoologist, public official, and businessman
Joseph Emerson Worcester (1784–1865), American lexicographer
Noah Worcester (1758-1837), American peace activist
Robert Worcester (born 1933), founder of Market and Opinion Research International Ltd.
Samuel Worcester (1798-1859), American missionary to the Cherokees
Samuel Worcester (theologian) (1770-1821), Unitarian controversialist
Samuel T. Worcester (1804-1882), American politician
Tracy Worcester (born 1958), English actress and environmental activist
William Worcester (c. 1415–c. 1482), English chronicler and antiquary