Wittwer is a surname. Notable people with the surname include:
Andreas Wittwer (born 1990), Swiss professional footballer
Michael Wittwer (born 1967), German footballer
Otto Wittwer (born 1937), Swiss professional ice hockey player
Stefan Wittwer (born 1971), Swiss nordic skier
Sylvan Wittwer (1917–2012), American agronomist
Uwe Wittwer (born 1954), Swiss artist