Wise is a surname. Notable people with the surname include:
Audrey Wise (1935–2000), United Kingdom politician
Bob Wise (born 1948), American politician
Brownie Wise (1913–1992), American saleswoman who developed "party plan" marketing
Christopher Wise (born 1961), American author
Cody Wise, American singer
David Wise (composer), British video game music composer
Deatrich Wise (born 1965), American football player
Dennis Wise (born 1966), English footballer
DeWayne Wise (born 1978), American baseball player
Doc Wise (born 1967), American football player
Ernie Wise (1925–1999), British comedian
George D. Wise (1831–1908), American politician and Confederate army captain
George D. Wise (Union) (1816–1881), American Union brevet brigadier general
George S. Wise (1906-1987), Polish-American scholar
Glenn M. Wise American politician
Henry Wise (disambiguation), several people
Henry A. Wise (1806–1876), American politician
Henry Augustus Wise (1819-1869), American naval officer
Isaac Mayer Wise (1819–1900), American Reform rabbi and author
John Wise (clergyman) (1652–1725)
John Wise (Canadian politician) (born 1935)
John Wise (balloonist) (1808–1879)
John Sergeant Wise (1846–1913), American Congressman
Josh Wise (born 1983), NASCAR driver
Kurt Wise, American creationist
Mark B. Wise (born 1953), physicist
Matt Wise (born 1975), baseball player
Michael Wise (disambiguation), several people
Ray Wise (born 1947), American actor
Rick Wise (born 1945), baseball player
Robert Wise (1914–2005), American film producer and director
Seelig Wise (1913-2004), American farmer and politician
Stephen Samuel Wise (1862–1949), American rabbi and Zionist
Steven M. Wise, author
Tim Wise, American anti-racist activist
Thomas Wise (disambiguation), several people
Tom Wise (born 1948), Member of the European Parliament
