Winthrop is a surname. Notable persons with that surname include:
Beekman Winthrop (1874–1940), New York lawyer and Governor of Puerto Rico
Clara Winthrop (1876–after 1935), American philanthropist
John Winthrop (c. 1587–1649), founding governor of the Massachusetts Bay Colony
John Winthrop, the Younger (1606–1676), governor of Connecticut
John Winthrop (educator) John Winthrop (1714–1779), American astronomer and professor at Harvard College
Robert Charles Winthrop (1809–1894), American lawyer and philanthropist
Theodore Winthrop (1828–1861), American writer, lawyer, and world traveller
Thomas L. Winthrop (1760–1841), American Lieutenant Governor of Massachusetts