Winsome is a given name, and may refer to:
Winsome Andante (born 1993), English eventing horse
Winsome Brown (born 1973), Obie-award winning NYC-based actress and writer
Winsome Evans (born 1941), Australian early music specialist
Winsome McCaughey, Lord Mayor of Melbourne from 1988-1989
Winsome Pinnock (born 1961), British playwright
Winsome Sears (born 1964), American politician
Winsome Witch, fictional title character of an animated cartoon series