Winona is a feminine given name, an Anglicized form of the Dakota descriptive term, Winúŋna, meaning "firstborn daughter."
People with the name or variations thereof include:
The daughter of the Dakota Sioux Chief Wapasha III, sometimes identified with the legendary figure, Winona
Winona LaDuke (born 1959), Native American activist
Winona Ryder (born 1971), American actress
Wynona Carr (1924–76), African-American gospel, R&B and rock and roll singer-songwriter
Wynona Lipman (c. 1932–99), American politician and New Jersey state senator
Wynonna Judd (born 1964), American country singer
Fictional characters so named include:
Wenonah, the mother of Hiawatha in Longfellow's epic poem The Song of Hiawatha (1855)
Winona, a character in the Pokémon universe
Winona Kirk, the mother of Star Trek's James T. Kirk