Wilkens is a surname. Notable people with the surname include:
Andrea Wilkens (born 1984), German footballerCarl Wilkens (born c. 1957), American involved in genocide rescue effortsElmer Wilkens (1901–1967), American football player who played in the National Football LeagueHenry Wilkens (1855–1895), American Medal of Honor recipientIman Wilkens (born 1936), author of Where Troy Once StoodJan Wilkens (born 1943), South African wrestlerLenny Wilkens (born 1937), American basketball player and coachPiter Wilkens (born 1959), Dutch musicianTheodoor Wilkens (1690–1748), painter from the Northern NetherlandsTom Wilkens (born 1975), American competitive swimmerToni Wilkens (born 1962), Swedish actorWilhelm Wilkens (1893–1967), Swedish rower