Wilken is a surname. Notable people with the surname include:
Aud Wilken (born 1965), Danish singerCharles Wilken (1866–1956), Danish actorClaudia Ann Wilken (born 1949), United States federal judgeDorothy Wilken, American politicianFriedrich Wilken (1777–1840), German librarian, historian and orientalistHermann Wilken (1522–1603), German humanist and mathematicianPatrick Wilken (born 1966), Australian scientist and editorStewart Wilken (born 1966), South African serial killer