Widdrington is a surname, and may refer to:
The various barons Widdrington, including:
William Widdrington, 1st Baron Widdrington (1610 – 1651)
His great-grandson William Widdrington, 4th Baron Widdrington (1678 – 1743)
The 1st Baron's relative Sir Thomas Widdrington, and Thomas's brother Ralph
Tommy Widdrington (born 1971), English-born footballer who played for Southampton and Port Vale
Thomas Preston (Benedictine monk), adopted the name of Roger Widdrington
Samuel Edward Cook (writer), took the name of Widdrington, his mother being the heiress of some of the estates of this family