Wertheim is a German surname. Notable people with the surname include:
Abraham Carel Wertheim (1832-1897), Dutch banker and philanthropist
Dick Wertheim (died 1983), American tennis linesman
Eric Wertheim (born 1973), American naval expert, columnist and author
Ernst Wertheim (1864-1920), Austrian gynecologist
Georg Wertheim (1857–1939), German merchant
Géza Wertheim (1910-after 1957), Luxembourgian tennis player and bobsledder
Guillame Wertheim, see Wiedemann effect
Herbert Wertheim, American inventor, scientist, educator and clinician
John Wertheim (born 1968), American lawyer and politician
Juliusz Wertheim (1880-1928), Polish pianist, conductor and composer
L. Jon Wertheim (born 1970), American sports journalist and author
Lucy Wertheim (1883–1971), English art dealer
Margaret Wertheim (born 1958), Australian international science writer and commentator
Maurice Wertheim (1886–1950), American investment banker, chess player, and philanthropist
Micha Wertheim (born 1972), Dutch stand-up comedian and satirist
Pierre Wertheim (1888-1971), French World War I flying ace
Rosy Wertheim (1888-1949), Dutch pianist, music educator and composer
Theodor Wertheim (1820-1864), Austrian chemist
