Welser is a surname. Notable people with the surname include:
Bartholomeus V. Welser (c. 1475 – 1559), Augsburg merchant and banker
Bartholomeus VI. Welser (1512 - 1546), explorer of Venezuela
Carl Wilhelm Welser von Neunhof (1663–1711), mayor of Nuremberg
Franz Welser-Möst (born 1960), Austrian conductor, music director of the Cleveland Orchestra
Philippine Welser (1527–1580), morganatic wife of Ferdinand II, Archduke of Austria