Weddell is a surname. Notable people with the surname include:
Alan Weddell, American college football coach
Alexander W. Weddell (1876–1948), American diplomat; ambassador to Argentina and Spain
Hugh Algernon Weddell (1819–1877), English botanist
James Weddell (1787–1834), English navigator and Antarctic explorer; eponym of Weddell Sea, Weddell Island, Weddell Glacier, and Weddell seal
Robert Weddell (1882–1951), Australian soldier and politician