Wasson is a surname. Notable people with the surname include:
Craig Wasson (born 1954), American actor
Daniel Wasson
David Wasson
Dean Wasson
Erin Wasson
Ernie Wasson
Gus Wasson
Isabel Bassett Wasson, American geologist and naturalist
Jeremiah Richard Wasson (1855–1913), American military instructor in 19th century Japan
Robert Gordon Wasson (1898–1986), American banker who became an expert on psilocybe mushrooms
Thomas C. Wasson, American Consul General in Jerusalem, 1948
William Wasson, American priest