Species Human Entrez 65267 | Human Mouse Ensembl ENSG00000196632 | |
Aliases WNK3, PRKWNK lysine deficient protein kinase 3 External IDs MGI: 2652875 HomoloGene: 32493 GeneCards: WNK3 | ||
Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a protein that in humans is encoded by the WNK3 gene.
Function
WNK3 is a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase 3 dependent pathway.
References
WNK3 Wikipedia(Text) CC BY-SA