WNK3

Updated on Jan 01, 2025

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Species Human Entrez 65267		Human Mouse Ensembl ENSG00000196632
Aliases WNK3, PRKWNK lysine deficient protein kinase 3 External IDs MGI: 2652875 HomoloGene: 32493 GeneCards: WNK3

Serine/threonine-protein kinase WNK3, also known as protein kinase lysine-deficient 3, is a protein that in humans is encoded by the WNK3 gene.

Function

WNK3 is a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca²⁺ transport pathway, and it plays a role in the increase of cell survival in a caspase 3 dependent pathway.

References

WNK3 Wikipedia

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