Species Human Entrez 49856 | Human Mouse Ensembl ENSG00000116213 | |
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Aliases WRAP73, WDR8, WD repeat containing, antisense to TP73 External IDs MGI: 1891749 HomoloGene: 9857 GeneCards: WRAP73 | ||
WD repeat-containing protein 8 is a protein that in humans is encoded by the WDR8 gene.
Function
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This family member is 89% identical to the mouse Wdr8 protein at the amino acid level. The function of this protein is not known, and the mouse studies suggest that the Wdr8 protein may play a role in the process of ossification.
References
WDR8 Wikipedia(Text) CC BY-SA