Vomifoliol dehydrogenase

In enzymology, a vomifoliol dehydrogenase (EC 1.1.1.221) is an enzyme that catalyzes the chemical reaction

(6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD⁺ ⇌ (6R)-6-hydroxy-3-oxo-alpha-ionone + NADH + H⁺

Thus, the two substrates of this enzyme are (6S,9R)-6-hydroxy-3-oxo-alpha-ionol and NAD⁺, whereas its 3 products are (6R)-6-hydroxy-3-oxo-alpha-ionone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is vomifoliol:NAD⁺ oxidoreductase. Other names in common use include vomifoliol 4'-dehydrogenase, and vomifoliol:NAD⁺ 4'-oxidoreductase.