Kalpana Kalpana (Editor)

Volociximab

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Type
  
Whole antibody

Target
  
α5β1 integrin

CAS Number
  
558480-40-3

Source
  
Chimeric (mouse/human)

ATC code
  
none

ChemSpider
  
none

Volociximab (also known as M200) is a chimeric monoclonal antibody jointly developed by PDL BioPharma and Biogen Idec for treatment of a variety of advanced solid tumors. It binds to and inhibits the functional activity of α5β1 integrin.

It is thought to reduce metastases. Early results show potential in renal cell cancers.

References

Volociximab Wikipedia