Puneet Varma (Editor)

Vinylacetyl CoA Delta isomerase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
5.3.3.3

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9023-73-8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a vinylacetyl-CoA Delta-isomerase (EC 5.3.3.3) is an enzyme that catalyzes the chemical reaction

vinylacetyl-CoA crotonyl-CoA

Hence, this enzyme has one substrate, vinylacetyl-CoA, and one product, crotonyl-CoA.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is vinylacetyl-CoA Delta3-Delta2-isomerase. Other names in common use include vinylacetyl coenzyme A Delta-isomerase, vinylacetyl coenzyme A isomerase, and Delta3-cis-Delta2-trans-enoyl-CoA isomerase. This enzyme participates in butanoate metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U8V.

References

Vinylacetyl-CoA Delta-isomerase Wikipedia