Verhoeff is a surname. Notable people with the surname include:
Frederick Herman Verhoeff (1874–1968), American ophthalmic surgeon who developed Verhoeff's stainHendrik Verhoeff (c. 1645 – c. 1680), Dutch silversmith and assassinJacobus Verhoeff (b. 1927), a Dutch mathematicianJohn M. Verhoeff, of the Peary expedition to Greenland of 1891–92Karl Wilhelm Verhoeff (1867–1945), a German zoologistPieter Verhoeff (b. 1938), a Dutch film directorPieter Willemsz. Verhoeff (c. 1573–1609), Dutch captain of the Admiralty of Amsterdam