Vane is a surname. Notable people with the surname include:
Charles Vane (c.1680–1721), English pirate who preyed upon English and French shipping. His pirate career lasted from 1716–1719Charles Vane-Tempest-Stewart, 6th Marquess of Londonderry (1852–1915), British Conservative politicianCharles Vane-Tempest-Stewart, 7th Marquess of Londonderry (1878–1949), Secretary of State for Air in the 1930s, in favour of the appeasement policy towards Nazi GermanChristopher Vane, 1st Baron Barnard (1653–1723), English peer known for his treatment of his heirs, and his employment as steward of Peter Smart; father of the poet Christopher SmartEdith Vane-Tempest-Stewart, Marchioness of Londonderry (1878–1959), a noted socialite and philanthropist in the United Kingdom between World War I and World War IISir Francis Vane, Baronet, (1861–1934), early aide of Lord Baden-Powell's and a Scout Commissioner of London before Baden-Powell ousted him from the Scout Association; founder of the Order of World Scouts, the earliest multinational Scouting movementGeorge Vane-Tempest, 5th Marquess of Londonderry (1821–1884), Anglo-Irish aristocrat, businessman and Conservative politicianHarry Vane, 11th Baron Barnard (born September 21, 1923), British peer, the son of Christopher Vane, 10th Baron BarnardHenry Vane:Sir Henry Vane the Elder (1589–1655), English courtier, father of Henry Vane the YoungerSir Henry Vane the Younger (1613–1662), statesman, Puritan, son of Henry Vane the ElderHenry Vane, 1st Earl of Darlington (c. 1705–1758) (c. 1705 – 6 March 1758), an English peer, the son of Gilbert Vane, 2nd Baron BarnardHenry Vane, 2nd Earl of Darlington (1726–1792), English peer, the son of the 1st EarlJohn Robert Vane (1927–2004), English pharmacologist, born in Tardebigg, WorcestershireMark Sutton Vane, English architectural lighting designerRichard Fletcher-Vane, 2nd Baron Inglewood (b. 1951), Conservative Party politician in the United Kingdom, Member of the European Parliament (MEP) for Cumbria and Lancashire North from 1989 to 1994, and for North West England from 1999 to 2004Robin Vane-Tempest-Stewart, 8th Marquess of Londonderry (1902–1955), Irish peer and politicianWilliam Vane, 1st Duke of Cleveland (1766–1842), British peerWilliam Fletcher-Vane, 1st Baron Inglewood (1909–1989), British politicianZachary A. Vane, American politician