van Kessel is a surname. Notable people with the surname include:
Gino van Kessel (born 1993), Curaçaoan footballer
Henk van Kessel (born 1946), Dutch motorcycle racer
Jan van Kessel (Amsterdam) (1641–1680), Dutch Golden Age painter
Jan van Kessel the Younger (1654–1708), Flemish Baroque painter
Jan van Kessel the Elder (1626–idem, 1679), Flemish painter
John Van Kessel (born 1969), Canadian ice hockey player
Lieve van Kessel (born 1977), Dutch field hockey player
