Van Dyck or Vandyck is a Dutch surname. Notable people with the surname include:
Anthony van Dyck (1599–1641), Flemish artist, or the van Dyck beard named after himCornelius Van Alen Van Dyck (1819–1895), American missionaryEdouard Van Dyck (1918–1977), Belgian professional road bicycle racerElisabeth Van Dyck (1951–1979), German member of the Red Army FactionErnest van Dyck (1861–1923), Belgian dramatic tenorFloris van Dyck (1575–1651), Dutch painterHenry H. Van Dyck (1809–1888), New York politicianJeff van Dyck (born 1969), Australian video game music composerJennifer Van Dyck (born 1962), Scottish television and film actressSteve Van Dyck, Australian zoologist and museum curatorVedder Van Dyck (1889–1960), American Episcopal bishopWilliam Vandyck, British actor and children's authorWilliam V. B. Van Dyck (1875–1981), American football player, electrical engineer, and businessman